![]() These two enzymes play crucial roles in the metabolism of a wide variety of endogenous esters, ester-containing drugs and environmental toxicants. In the human body, two predominant carboxylesterases (CES1 and CES2) have been identified and extensively studied over the past decade. You’ll need a nice cold glass of wine when it’s all over and you’ll finally be able to collapse on the sofa in front of Netflix in peace.Mammalian carboxylesterases (CEs) are key enzymes from the serine hydrolase superfamily. Instead of having pre-Christmas drinks with every group of friends & work colleagues, how about pushing some back to the New Year? This gives you a little pick me up when the Christmas cheer has faded. Relax by looking at what you can and can't do. It’s really difficult for children to maintain first rate behaviour when doing the rounds of friends and relatives and not everyone remembers what it’s like to have young children. If you have to see both yours and your partner’s families and a plethora of relatives to boot, why not arrange to see one set a few weeks before/after Christmas. If you want to hit the high street, book childcare so you can enjoy browsing and lunching without the whinging. Shop on the web and tie in with friends on 3 for 2’s. Limit gifts to children only or organise a secret Santa for the wider family or friendship groups. Rein in gift exchanges that have been outgrown or lost their meaning. Our everyday practices help calm and centre us. ![]() If escaping on a date night with your husband keeps you sane… keep it that way. If the kids need downtime or you like to read for half an hour before bed, don't give that up in favour of yet another Christmas chore. You can even delegate childcare to a babysitter so you have time to get those roots or nails done or just get the house or presents organised. And if you have visitors, they can help share the burden too. You can't do everything so divide chores between your family. Even planning meals on paper can prevent you from buying enough food to last you til Easter. With everything on your plate, it’s easy to buy a gift twice or miss someone off your list. ![]() Getting things down on paper can really help you stay sane in the silly season. You can even book a babysitter for the morning after the night before & recover in peace… bliss. Booking a babysitter an hour earlier than you need to be out the door gives the kids time to settle and you time to get ready without someone calling ‘Mum’. At the same time as you’re planning your party dress, don’t forget to book your childcare. Give yourself permission to reclaim a bit of festive fun & let go a little. Does the tree have to be hand-picked from an enchanted forest? Will it ruin Xmas day if you haven’t got 7 types of veg? Think back to the most magical memories you had as a child and they will likely be based on more simple rituals. ![]() Or just the ones they really love.Īsk, “If I don’t do this, what will happen?”. Drop expensive, high-stress rituals in favour of something simple. True, families thrive on traditions, but it's less about the event itself, which your kids may have outgrown, and more about time together. The panto, school concert, Elf on the shelf, grottos, carol singing, Santa train, Xmas eve box, Santa letter, home-made advent calendar… do you feel frazzled at just the thought of them? If you’ve over-planned but struggling to deliver - make a switch. Without a doubt your friends will be grateful you’re soothing their own guilt. No time to write Xmas cards and feeling anxious every time one drops on the mat? Ask yourself which are the 10 most important ones – maybe your great-aunt who’s not managed to master email? Try sending messages on social media or announce a donation to charity. So chill out, grab a coffee and read our top 11 tips for surviving the family Christmas madness (with your sanity intact). So if you’re pondering ways to cut stress, save money and tame over-the-top traditions, setting simplicity strategies in place early will keep you from being swept up in the festive madness. In contrast you’ve crawled up to the finishing line, roots showing, squeezed into your Spanx and feeling more frazzled than your turkey. Pressure mounts up trying to be Instagram perfect & you’re feeling inadequate when your timeline is full of Alpha playground mums with their handmade Xmas decs, Mary Berry puds & declarations of ‘presents all bought and wrapped’ in September. But as December rolls on it can turn from the ’most wonderful’ to the most stressful time of the year. ![]() Top 11 Tips for Staying Sane This Silly Seasonĭoes Christmas fill you with festive cheer? The John Lewis ad, hot mulled wine, Michael Buble on Spotify and the aroma of Starbucks’ latest latte. ![]()
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